Annotation Detail

Information
Associated Genes
GNAO1
Associated Variants
GNAO1 c.723+2T>A ( ENST00000262494.13, ENST00000638705.1, ENST00000568375.3, ENST00000262493.12, ENST00000640469.2 )
GNAO1 c.723+2T>A ( ENST00000262493.12, ENST00000262494.13, ENST00000568375.3, ENST00000638705.1, ENST00000640469.2 )
Associated Disease
neurodevelopmental disorder with involuntary movements
Source Database
ClinVar
Description
NM_020988.3(GNAO1):c.723+2T>A AND Neurodevelopmental disorder with involuntary movements
ClinVar Allele ID
1052635
ClinVar RefSeq Alternation Syntax
NM_020988.3:c.723+2T>A
ClinVar RefSeq Alternation Syntax
NM_138736.3:c.723+2T>A
Clinical Significance Description
Pathogenic
Clinical Significance Last Update
2021-06-02
Clinical Significance Review Status
no assertion criteria provided
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV001374408
ClinVar Disease
Neurodevelopmental disorder with involuntary movements
Observed Origin Sample
de novo
Drugs