Annotation Detail

Information
Associated Genes
TP63
Associated Variants
TP63 p.Leu616SerfsTer88 (p.L616Sfs*88) ( ENST00000264731.8, ENST00000320472.9, ENST00000354600.10, ENST00000440651.6, ENST00000449992.5, ENST00000456148.1 )
TP63 p.Leu616SerfsTer88 (p.L616Sfs*88) ( ENST00000264731.8, ENST00000320472.9, ENST00000354600.10, ENST00000440651.6, ENST00000449992.5, ENST00000456148.1 )
Associated Disease
TP63-Related Spectrum Disorders
Source Database
ClinVar
Description
NM_003722.5(TP63):c.1846del (p.Leu616fs) AND TP63-Related Spectrum Disorders
ClinVar Allele ID
47571
ClinVar RefSeq Alternation Syntax
NM_001329150.2:c.*74del
ClinVar RefSeq Alternation Syntax
NM_001114980.2:c.1564del
ClinVar RefSeq Alternation Syntax
NM_001329149.2:c.*74del
ClinVar RefSeq Alternation Syntax
NM_001329146.2:c.1309del
ClinVar RefSeq Alternation Syntax
NM_003722.5:c.1846del
ClinVar RefSeq Alternation Syntax
NM_001329144.2:c.*74del
ClinVar RefSeq Alternation Syntax
NM_001329964.2:c.1840del
ClinVar RefSeq Alternation Syntax
NM_001329145.2:c.*74del
ClinVar RefSeq Alternation Syntax
NM_001329148.2:c.1834del
ClinVar RefSeq Alternation Syntax
NM_001114978.2:c.*84del
ClinVar RefSeq Alternation Syntax
NM_001114981.2:c.*84del
Clinical Significance Description
Uncertain significance
Clinical Significance Last Update
2017-07-06
Clinical Significance Review Status
criteria provided, single submitter
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV001324952
ClinVar Disease
TP63-Related Spectrum Disorders
Observed Origin Sample
germline
Drugs