Annotation Detail

Information
Associated Genes
PEX2
Associated Variants
PEX2 p.Arg119Ter (p.R119*) ( ENST00000522527.5, ENST00000357039.9, ENST00000520103.5 )
PEX2 p.Arg119Ter (p.R119*) ( ENST00000357039.9, ENST00000520103.5, ENST00000522527.5 )
Associated Disease
Zellweger spectrum disorders
Source Database
ClinVar
Description
NM_000318.3(PEX2):c.355C>T (p.Arg119Ter) AND Zellweger spectrum disorders
ClinVar Allele ID
28743
ClinVar RefSeq Alternation Syntax
NM_001079867.2:c.355C>T
ClinVar RefSeq Alternation Syntax
NM_001172086.2:c.355C>T
ClinVar RefSeq Alternation Syntax
NM_000318.3:c.355C>T
ClinVar RefSeq Alternation Syntax
NM_001172087.2:c.355C>T
Clinical Significance Description
Pathogenic
Clinical Significance Last Update
2020-09-16
Clinical Significance Review Status
no assertion criteria provided
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV001275872
ClinVar Disease
Zellweger spectrum disorders
Observed Origin Sample
germline
Drugs