Annotation Detail

Information
Associated Genes
SGCA
Associated Variants
SGCA p.Arg284Gly (p.R284G) ( ENST00000504073.2, ENST00000262018.8, ENST00000682109.1, ENST00000344627.10 )
SGCA p.Arg284Gly (p.R284G) ( ENST00000262018.8, ENST00000344627.10, ENST00000504073.2, ENST00000682109.1 )
Associated Disease
autosomal recessive limb-girdle muscular dystrophy type 2D
Source Database
ClinVar
Description
NM_000023.4(SGCA):c.850C>G (p.Arg284Gly) AND Autosomal recessive limb-girdle muscular dystrophy type 2D
ClinVar Allele ID
958184
ClinVar RefSeq Alternation Syntax
NM_001135697.3:c.585-395C>G
ClinVar RefSeq Alternation Syntax
NM_000023.4:c.850C>G
Clinical Significance Description
Conflicting interpretations of pathogenicity
Clinical Significance Last Update
2023-11-07
Clinical Significance Review Status
criteria provided, conflicting interpretations
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV001248461
ClinVar Disease
Autosomal recessive limb-girdle muscular dystrophy type 2D
Observed Origin Sample
germline
Drugs