Annotation Detail

Information
Associated Genes
ABCA4
Associated Variants
ABCA4 p.Arg18Trp (p.R18W) ( ENST00000649773.1, ENST00000370225.4 )
ABCA4 p.Arg18Trp (p.R18W) ( ENST00000370225.4, ENST00000649773.1 )
Associated Disease
Retinal dystrophy
Source Database
ClinVar
Description
NM_000350.3(ABCA4):c.52C>T (p.Arg18Trp) AND Retinal dystrophy
ClinVar Allele ID
22938
ClinVar RefSeq Alternation Syntax
NM_000350.3:c.52C>T
ClinVar RefSeq Alternation Syntax
NM_001425324.1:c.52C>T
Clinical Significance Description
Pathogenic
Clinical Significance Last Update
2019-05-09
Clinical Significance Review Status
criteria provided, single submitter
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV001075717
ClinVar Disease
Retinal dystrophy
Observed Origin Sample
germline
Drugs