Annotation Detail

Information
Associated Genes
OPA1
Associated Variants
OPA1 p.Val940GlyfsTer3 (p.V940Gfs*3) ( ENST00000361150.6, ENST00000361510.8, ENST00000361715.6, ENST00000361828.7, ENST00000361908.8, ENST00000392436.7, ENST00000392437.6, ENST00000643329.1, ENST00000645553.1, ENST00000646793.1 )
OPA1 p.Val940GlyfsTer3 (p.V940Gfs*3) ( ENST00000361150.6, ENST00000361510.8, ENST00000361715.6, ENST00000361828.7, ENST00000361908.8, ENST00000392436.7, ENST00000392437.6, ENST00000643329.1, ENST00000645553.1, ENST00000646793.1 )
Associated Disease
Retinal dystrophy
Source Database
ClinVar
Description
NM_130837.3(OPA1):c.2873_2876del AND Retinal dystrophy
ClinVar Allele ID
20121
ClinVar RefSeq Alternation Syntax
NM_130837.3:c.2873_2876del
Clinical Significance Description
Pathogenic
Clinical Significance Last Update
2017-10-12
Clinical Significance Review Status
criteria provided, single submitter
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV001073751
ClinVar Disease
Retinal dystrophy
Observed Origin Sample
germline
Drugs