Annotation Detail
Information
- Associated Genes
- COMT
- Associated Variants
-
COMT p.Leu136= (p.L136=)
(
ENST00000361682.11,
ENST00000403184.5,
ENST00000403710.5,
ENST00000406520.7,
ENST00000407537.5,
ENST00000428707.2,
ENST00000449653.5,
ENST00000676678.1,
ENST00000678255.1,
ENST00000678769.1,
ENST00000678868.1 )
COMT p.Leu136= (p.L136=) ( ENST00000361682.11, ENST00000403184.5, ENST00000403710.5, ENST00000406520.7, ENST00000407537.5, ENST00000428707.2, ENST00000449653.5, ENST00000676678.1, ENST00000678255.1, ENST00000678769.1, ENST00000678868.1 ) - Source Database
- ClinVar
- Description
- NM_000754.4(COMT):c.408C>G (p.Leu136=) AND Tramadol response
- ClinVar Allele ID
- 257575
- ClinVar RefSeq Alternation Syntax
- NM_001135161.2:c.408C>G
- ClinVar RefSeq Alternation Syntax
- NM_001135162.2:c.408C>G
- ClinVar RefSeq Alternation Syntax
- NM_001362828.2:c.408C>G
- ClinVar RefSeq Alternation Syntax
- NM_007310.3:c.258C>G
- ClinVar RefSeq Alternation Syntax
- NM_000754.4:c.408C>G
- Clinical Significance Description
- drug response
- Clinical Significance Last Update
- 2018-04-28
- Clinical Significance Review Status
- no assertion criteria provided
- URL
- https://www.ncbi.nlm.nih.gov/clinvar/RCV001029692
- Observed Origin Sample
- somatic
Drugs