Annotation Detail

Information
Associated Genes
NOTCH1 LOC126860794
Associated Variants
NOTCH1 p.Asp1989= (p.D1989=) ( ENST00000651671.1, ENST00000680133.1, ENST00000680218.1, ENST00000680668.1, ENST00000680778.1 )
NOTCH1 p.Asp1989= (p.D1989=) ( ENST00000651671.1, ENST00000680133.1, ENST00000680218.1, ENST00000680668.1, ENST00000680778.1 )
Associated Disease
Adams-Oliver syndrome 5
Source Database
ClinVar
Description
NM_017617.5(NOTCH1):c.5967T>C (p.Asp1989=) AND Adams-Oliver syndrome 5
ClinVar Allele ID
258566
ClinVar RefSeq Alternation Syntax
NM_017617.5:c.5967T>C
Clinical Significance Description
Benign
Clinical Significance Last Update
2023-10-23
Clinical Significance Review Status
criteria provided, multiple submitters, no conflicts
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000862614
ClinVar Disease
Adams-Oliver syndrome 5
Observed Origin Sample
germline
Drugs