Annotation Detail

Information
Associated Genes
GAA
Associated Variants
GAA p.Leu299Arg (p.L299R) ( ENST00000714054.1, ENST00000577106.6, ENST00000714057.1, ENST00000714062.1, ENST00000390015.7, ENST00000570803.6, ENST00000714058.1, ENST00000302262.8, ENST00000714055.1 )
GAA p.Leu299Arg (p.L299R) ( ENST00000302262.8, ENST00000390015.7, ENST00000570803.6, ENST00000577106.6, ENST00000714054.1, ENST00000714055.1, ENST00000714057.1, ENST00000714058.1, ENST00000714062.1 )
Associated Disease
Glycogen storage disease, type II
Source Database
ClinVar
Description
NM_000152.5(GAA):c.896T>G (p.Leu299Arg) AND Glycogen storage disease, type II
ClinVar Allele ID
19064
ClinVar RefSeq Alternation Syntax
NM_001079803.3:c.896T>G
ClinVar RefSeq Alternation Syntax
NM_001079804.3:c.896T>G
ClinVar RefSeq Alternation Syntax
NM_000152.5:c.896T>G
Clinical Significance Description
Likely pathogenic
Clinical Significance Last Update
2022-05-11
Clinical Significance Review Status
reviewed by expert panel
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000795023
ClinVar Disease
Glycogen storage disease, type II
Observed Origin Sample
germline
Drugs