Annotation Detail

Information
Associated Genes
MYH7
Associated Variants
MYH7 p.Asp239Asn (p.D239N) ( ENST00000713769.1, ENST00000713768.1, ENST00000355349.4 )
MYH7 p.Asp239Asn (p.D239N) ( ENST00000355349.4, ENST00000713768.1, ENST00000713769.1 )
Associated Disease
hypertrophic cardiomyopathy
Source Database
ClinVar
Description
NM_000257.4(MYH7):c.715G>A (p.Asp239Asn) AND Hypertrophic cardiomyopathy
ClinVar Allele ID
52270
ClinVar RefSeq Alternation Syntax
NM_000257.4:c.715G>A
Clinical Significance Description
Likely pathogenic
Clinical Significance Last Update
2021-03-22
Clinical Significance Review Status
reviewed by expert panel
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000628940
ClinVar Disease
Hypertrophic cardiomyopathy
Observed Origin Sample
germline
Drugs