Annotation Detail

Information
Associated Genes
EGFR
Associated Variants
EGFR p.Ser492Arg (p.S492R) ( ENST00000275493.7, ENST00000342916.7, ENST00000344576.7, ENST00000450046.2, ENST00000455089.5 )
EGFR p.Ser492Arg (p.S492R) ( ENST00000275493.7, ENST00000342916.7, ENST00000344576.7, ENST00000450046.2, ENST00000455089.5 )
Associated Disease
Neoplasm of the large intestine
Source Database
ClinVar
Description
NM_005228.5(EGFR):c.1476C>A (p.Ser492Arg) AND Neoplasm of the large intestine
ClinVar Allele ID
363220
ClinVar RefSeq Alternation Syntax
NM_001346897.2:c.1341C>A
ClinVar RefSeq Alternation Syntax
NM_001346899.2:c.1341C>A
ClinVar RefSeq Alternation Syntax
NM_001346900.2:c.1317C>A
ClinVar RefSeq Alternation Syntax
NM_201284.2:c.1476C>A
ClinVar RefSeq Alternation Syntax
NM_001346898.2:c.1476C>A
ClinVar RefSeq Alternation Syntax
NM_001346941.2:c.675C>A
ClinVar RefSeq Alternation Syntax
NM_005228.5:c.1476C>A
ClinVar RefSeq Alternation Syntax
NM_201282.2:c.1476C>A
Clinical Significance Description
not provided
Clinical Significance Last Update
2016-03-10
Clinical Significance Review Status
no assertion provided
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000423834
ClinVar Disease
Neoplasm of the large intestine
Observed Origin Sample
somatic
Drugs