Annotation Detail

Information
Associated Genes
INS INS-IGF2
Associated Variants
INS p.Thr51= (p.T51=), INS-IGF2 p.Thr51= (p.T51=) ( ENST00000512523.1, ENST00000250971.7, ENST00000397262.5, ENST00000397270.1, ENST00000381330.5 )
INS p.Thr51= (p.T51=), INS-IGF2 p.Thr51= (p.T51=) ( ENST00000250971.7, ENST00000381330.5, ENST00000397262.5, ENST00000512523.1, ENST00000397270.1 )
Associated Disease
maturity-onset diabetes of the young type 10
Source Database
ClinVar
Description
NM_000207.3(INS):c.153A>G (p.Thr51=) AND Maturity-onset diabetes of the young type 10
ClinVar Allele ID
313620
ClinVar RefSeq Alternation Syntax
NM_001185097.2:c.153A>G
ClinVar RefSeq Alternation Syntax
NM_000207.3:c.153A>G
ClinVar RefSeq Alternation Syntax
NM_001185098.2:c.153A>G
ClinVar RefSeq Alternation Syntax
NM_001042376.3:c.153A>G
ClinVar RefSeq Alternation Syntax
NM_001291897.2:c.153A>G
ClinVar RefSeq Alternation Syntax
NR_003512.4:n.212A>G
Clinical Significance Description
Likely benign
Clinical Significance Last Update
2017-09-29
Clinical Significance Review Status
criteria provided, single submitter
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000353376
ClinVar Disease
Maturity-onset diabetes of the young type 10
Observed Origin Sample
germline
Drugs