Annotation Detail

Information
Associated Genes
COL2A1
Associated Variants
COL2A1 p.Arg515= (p.R515=) ( ENST00000337299.7, ENST00000380518.8 )
COL2A1 p.Arg515= (p.R515=) ( ENST00000337299.7, ENST00000380518.8 )
Associated Disease
Stickler syndrome type 1
Source Database
ClinVar
Description
NM_001844.5(COL2A1):c.1545C>A (p.Arg515=) AND Stickler syndrome type 1
ClinVar Allele ID
254554
ClinVar RefSeq Alternation Syntax
NM_001844.5:c.1545C>A
ClinVar RefSeq Alternation Syntax
NM_033150.3:c.1338C>A
Clinical Significance Description
Likely benign
Clinical Significance Last Update
2018-01-13
Clinical Significance Review Status
criteria provided, single submitter
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000352106
ClinVar Disease
Stickler syndrome type 1
Observed Origin Sample
germline
Drugs