Annotation Detail

Information
Associated Genes
SMPD1
Associated Variants
SMPD1 p.Ala359Asp (p.A359D) ( ENST00000342245.9, ENST00000527275.5 )
SMPD1 p.Ala359Asp (p.A359D) ( ENST00000342245.9, ENST00000527275.5 )
Associated Disease
Sphingomyelin/cholesterol lipidosis
Source Database
ClinVar
Description
NM_000543.5(SMPD1):c.1076C>A (p.Ala359Asp) AND Sphingomyelin/cholesterol lipidosis
ClinVar Allele ID
199818
ClinVar RefSeq Alternation Syntax
NM_001318088.2:c.115C>A
ClinVar RefSeq Alternation Syntax
NM_001007593.3:c.1073C>A
ClinVar RefSeq Alternation Syntax
NR_027400.3:n.1201C>A
ClinVar RefSeq Alternation Syntax
NM_001318087.2:c.1076C>A
ClinVar RefSeq Alternation Syntax
NM_001365135.2:c.1076C>A
ClinVar RefSeq Alternation Syntax
NM_000543.5:c.1076C>A
Clinical Significance Description
not provided
Clinical Significance Review Status
no assertion provided
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000192224
ClinVar Disease
Sphingomyelin/cholesterol lipidosis
Observed Origin Sample
germline
Drugs