Annotation Detail

Information
Associated Genes
MYH7
Associated Variants
MYH7 p.Leu267Val (p.L267V) ( ENST00000713769.1, ENST00000355349.4, ENST00000713768.1 )
MYH7 p.Leu267Val (p.L267V) ( ENST00000355349.4, ENST00000713768.1, ENST00000713769.1 )
Associated Disease
hypertrophic cardiomyopathy
Source Database
ClinVar
Description
NM_000257.4(MYH7):c.799C>G (p.Leu267Val) AND Hypertrophic cardiomyopathy
ClinVar Allele ID
175506
ClinVar RefSeq Alternation Syntax
NM_000257.4:c.799C>G
Clinical Significance Description
Likely pathogenic
Clinical Significance Last Update
2015-09-21
Clinical Significance Review Status
criteria provided, single submitter
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000154595
ClinVar Disease
Hypertrophic cardiomyopathy
Observed Origin Sample
germline
Drugs