Annotation Detail

Information
Associated Genes
EGFR
Associated Variants
EGFR p.Gly719Arg (p.G719R) ( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 )
EGFR p.Gly719Arg (p.G719R) ( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 )
Associated Disease
Squamous cell carcinoma of the head and neck
Source Database
ClinVar
Description
NM_005228.5(EGFR):c.2155G>C (p.Gly719Arg) AND Squamous cell carcinoma of the head and neck
ClinVar Allele ID
54391
ClinVar RefSeq Alternation Syntax
NM_001346941.2:c.1354G>C
ClinVar RefSeq Alternation Syntax
NM_001346900.2:c.1996G>C
ClinVar RefSeq Alternation Syntax
NM_001346897.2:c.2020G>C
ClinVar RefSeq Alternation Syntax
NM_001346898.2:c.2155G>C
ClinVar RefSeq Alternation Syntax
NM_001346899.2:c.2020G>C
ClinVar RefSeq Alternation Syntax
NM_005228.5:c.2155G>C
Clinical Significance Description
drug response
Clinical Significance Review Status
no assertion criteria provided
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000114405
ClinVar Disease
Squamous cell carcinoma of the head and neck
Observed Origin Sample
not provided
Drugs