Annotation Detail

Information
Associated Genes
INS INS-IGF2
Associated Variants
INS p.Gly84Arg (p.G84R), INS-IGF2 c.187+850G>A ( ENST00000250971.7, ENST00000397262.5, ENST00000381330.5, ENST00000397270.1, ENST00000512523.1 )
INS p.Gly84Arg (p.G84R), INS-IGF2 c.187+850G>A ( ENST00000250971.7, ENST00000381330.5, ENST00000397262.5, ENST00000512523.1, ENST00000397270.1 )
Associated Disease
permanent neonatal diabetes mellitus
Source Database
ClinVar
Description
NM_000207.3(INS):c.250G>A (p.Gly84Arg) AND Permanent neonatal diabetes mellitus
ClinVar Allele ID
79621
ClinVar RefSeq Alternation Syntax
NM_001185097.2:c.250G>A
ClinVar RefSeq Alternation Syntax
NM_000207.3:c.250G>A
ClinVar RefSeq Alternation Syntax
NM_001185098.2:c.250G>A
ClinVar RefSeq Alternation Syntax
NM_001291897.2:c.250G>A
ClinVar RefSeq Alternation Syntax
NM_001042376.3:c.187+850G>A
Clinical Significance Description
not provided
Clinical Significance Review Status
no assertion provided
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000059611
ClinVar Disease
Permanent neonatal diabetes mellitus
Observed Origin Sample
not provided
Drugs