Annotation Detail

Information
Associated Genes
HNF1A
Associated Variants
HNF1A p.Leu562Phe (p.L562F) ( ENST00000541395.5, ENST00000257555.11, ENST00000544413.2 )
HNF1A p.Leu562Phe (p.L562F) ( ENST00000257555.11, ENST00000541395.5, ENST00000544413.2 )
Associated Disease
maturity-onset diabetes of the young type 3
Source Database
ClinVar
Description
NM_000545.8(HNF1A):c.1663C>T (p.Leu555Phe) AND Maturity-onset diabetes of the young type 3
ClinVar Allele ID
45469
ClinVar RefSeq Alternation Syntax
NM_000545.8:c.1663C>T
ClinVar RefSeq Alternation Syntax
NM_001306179.2:c.1684C>T
Clinical Significance Description
Conflicting interpretations of pathogenicity
Clinical Significance Last Update
2020-01-22
Clinical Significance Review Status
criteria provided, conflicting interpretations
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000030488
ClinVar Disease
Maturity-onset diabetes of the young type 3
Observed Origin Sample
germline
Drugs