Annotation Detail

Information
Associated Genes
HNF1A
Associated Variants
HNF1A p.Leu44TrpfsTer111 (p.L44Wfs*111) ( ENST00000541395.5, ENST00000257555.11, ENST00000400024.6, ENST00000544413.2 )
HNF1A p.Leu44TrpfsTer111 (p.L44Wfs*111) ( ENST00000257555.11, ENST00000400024.6, ENST00000541395.5, ENST00000544413.2 )
Associated Disease
maturity-onset diabetes of the young type 3
Source Database
ClinVar
Description
NM_000545.8(HNF1A):c.130del (p.Leu44fs) AND Maturity-onset diabetes of the young type 3
ClinVar Allele ID
45459
ClinVar RefSeq Alternation Syntax
NM_000545.8:c.130del
ClinVar RefSeq Alternation Syntax
NM_001306179.2:c.130del
Clinical Significance Description
Pathogenic
Clinical Significance Last Update
2011-08-18
Clinical Significance Review Status
criteria provided, single submitter
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000030478
ClinVar Disease
Maturity-onset diabetes of the young type 3
Observed Origin Sample
germline
Drugs