Annotation Detail

Information
Associated Genes
COL2A1
Associated Variants
COL2A1 p.Gly1047AlafsTer83 (p.G1047Afs*83) ( ENST00000337299.7, ENST00000380518.8 )
COL2A1 p.Gly1047AlafsTer83 (p.G1047Afs*83) ( ENST00000337299.7, ENST00000380518.8 )
Associated Disease
Stickler syndrome type 1
Source Database
ClinVar
Description
NM_001844.5(COL2A1):c.3138del (p.Gly1047fs) AND Stickler syndrome type 1
ClinVar Allele ID
32404
ClinVar RefSeq Alternation Syntax
NM_001844.5:c.3138del
ClinVar RefSeq Alternation Syntax
NM_033150.3:c.2931del
Clinical Significance Description
Pathogenic
Clinical Significance Last Update
1993-07-01
Clinical Significance Review Status
no assertion criteria provided
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000018909
ClinVar Disease
Stickler syndrome type 1
Observed Origin Sample
germline
Pubmed
8406454
Drugs