Annotation Detail

Information
Associated Genes
FGFR3
Associated Variants
FGFR3 p.Arg623His (p.R623H) ( ENST00000481110.7, ENST00000340107.9, ENST00000352904.6, ENST00000412135.7, ENST00000440486.8 )
FGFR3 p.Arg623His (p.R623H) ( ENST00000340107.9, ENST00000352904.6, ENST00000412135.7, ENST00000440486.8, ENST00000481110.7 )
Associated Disease
camptodactyly-tall stature-scoliosis-hearing loss syndrome
Source Database
ClinVar
Description
NM_000142.5(FGFR3):c.1862G>A (p.Arg621His) AND Camptodactyly-tall stature-scoliosis-hearing loss syndrome
ClinVar Allele ID
31394
ClinVar RefSeq Alternation Syntax
NM_000142.5:c.1862G>A
ClinVar RefSeq Alternation Syntax
NM_022965.4:c.1526G>A
ClinVar RefSeq Alternation Syntax
NR_148971.2:n.2288G>A
ClinVar RefSeq Alternation Syntax
NM_001163213.2:c.1868G>A
ClinVar RefSeq Alternation Syntax
NM_001354810.2:c.1865G>A
ClinVar RefSeq Alternation Syntax
NM_001354809.2:c.1865G>A
Clinical Significance Description
Pathogenic
Clinical Significance Last Update
2006-11-01
Clinical Significance Review Status
no assertion criteria provided
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000017765
ClinVar Disease
Camptodactyly-tall stature-scoliosis-hearing loss syndrome
Observed Origin Sample
germline
Pubmed
17033969
Drugs