Annotation Detail

Information
Associated Genes
ATP1A3
Associated Variants
ATP1A3 p.Ile287Thr (p.I287T), ENSG00000285505 p.Ile274Thr (p.I274T) ( ENST00000543770.5, ENST00000545399.6, ENST00000602133.5, ENST00000648268.1 )
ATP1A3 p.Ile287Thr (p.I287T), ENSG00000285505 p.Ile274Thr (p.I274T) ( ENST00000543770.5, ENST00000545399.6, ENST00000602133.5, ENST00000648268.1 )
Associated Disease
dystonia 12
Source Database
ClinVar
Description
NM_152296.5(ATP1A3):c.821T>C (p.Ile274Thr) AND Dystonia 12
ClinVar Allele ID
27949
ClinVar RefSeq Alternation Syntax
NM_001256214.2:c.860T>C
ClinVar RefSeq Alternation Syntax
NM_001256213.2:c.854T>C
ClinVar RefSeq Alternation Syntax
NM_152296.5:c.821T>C
Clinical Significance Description
Pathogenic
Clinical Significance Last Update
2004-07-22
Clinical Significance Review Status
no assertion criteria provided
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000013773
ClinVar Disease
Dystonia 12
Observed Origin Sample
germline
Pubmed
15260953
Drugs