Annotation Detail

Information
Associated Genes
CASR
Associated Variants
CASR p.Cys592Phe (p.C592F) ( ENST00000490131.7, ENST00000498619.4, ENST00000638421.1, ENST00000639785.2 )
CASR p.Cys592Phe (p.C592F) ( ENST00000490131.7, ENST00000498619.4, ENST00000638421.1, ENST00000639785.2 )
Associated Disease
familial hypocalciuric hypercalcemia 1
Source Database
ClinVar
Description
NM_000388.4(CASR):c.1745G>T (p.Cys582Phe) AND Familial hypocalciuric hypercalcemia 1
ClinVar Allele ID
23395
ClinVar RefSeq Alternation Syntax
NM_000388.4:c.1745G>T
ClinVar RefSeq Alternation Syntax
NM_001178065.2:c.1775G>T
Clinical Significance Description
Pathogenic
Clinical Significance Last Update
2007-11-01
Clinical Significance Review Status
no assertion criteria provided
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000008861
ClinVar Disease
Familial hypocalciuric hypercalcemia 1
Observed Origin Sample
germline
Pubmed
17698911
Drugs