Annotation Detail

Information
Associated Genes
RAPSN
Associated Variants
RAPSN p.Leu283Pro (p.L283P) ( ENST00000298854.7, ENST00000529341.1, ENST00000352508.7, ENST00000524487.5 )
RAPSN p.Leu283Pro (p.L283P) ( ENST00000298854.7, ENST00000352508.7, ENST00000524487.5, ENST00000529341.1 )
Associated Disease
congenital myasthenic syndrome 11
Source Database
ClinVar
Description
NM_005055.5(RAPSN):c.848T>C (p.Leu283Pro) AND Congenital myasthenic syndrome 11
ClinVar Allele ID
23091
ClinVar RefSeq Alternation Syntax
NM_005055.5:c.848T>C
ClinVar RefSeq Alternation Syntax
NM_032645.5:c.789+148T>C
Clinical Significance Description
Pathogenic
Clinical Significance Last Update
2006-10-10
Clinical Significance Review Status
no assertion criteria provided
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000008518
ClinVar Disease
Congenital myasthenic syndrome 11
Observed Origin Sample
germline
Pubmed
16931511
Drugs