Annotation Detail

Information
Associated Genes
TGFBI
Associated Variants
TGFBI p.Arg555Gln (p.R555Q) ( ENST00000442011.7 )
TGFBI p.Arg555Gln (p.R555Q) ( ENST00000442011.7 )
Associated Disease
Thiel-Behnke corneal dystrophy
Source Database
ClinVar
Description
NM_000358.3(TGFBI):c.1664G>A (p.Arg555Gln) AND Thiel-Behnke corneal dystrophy
ClinVar Allele ID
22906
ClinVar RefSeq Alternation Syntax
NM_000358.3:c.1664G>A
Clinical Significance Description
Pathogenic
Clinical Significance Last Update
2021-09-22
Clinical Significance Review Status
criteria provided, single submitter
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000008316
ClinVar Disease
Thiel-Behnke corneal dystrophy
Observed Origin Sample
germline
Pubmed
9780098
Pubmed
9054935
Pubmed
11923233
Pubmed
22355247
Drugs