Annotation Detail

Information
Associated Genes
GALT
Associated Variants
GALT p.Arg333Trp (p.R333W) ( ENST00000378842.8, ENST00000450095.6 )
GALT p.Arg333Trp (p.R333W) ( ENST00000378842.8, ENST00000450095.6 )
Associated Disease
Deficiency of UDPglucose-hexose-1-phosphate uridylyltransferase
Source Database
ClinVar
Description
NM_000155.4(GALT):c.997C>T (p.Arg333Trp) AND Deficiency of UDPglucose-hexose-1-phosphate uridylyltransferase
ClinVar Allele ID
18649
ClinVar RefSeq Alternation Syntax
NM_000155.4:c.997C>T
ClinVar RefSeq Alternation Syntax
NM_001258332.2:c.670C>T
Clinical Significance Description
Pathogenic/Likely pathogenic
Clinical Significance Last Update
2024-01-30
Clinical Significance Review Status
criteria provided, multiple submitters, no conflicts
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000003794
ClinVar Disease
Deficiency of UDPglucose-hexose-1-phosphate uridylyltransferase
Observed Origin Sample
germline
Observed Origin Sample
unknown
Pubmed
1897530
Pubmed
8943248
Drugs