Annotation Detail

Information
Associated Genes
VHL
Associated Variants
VHL p.Leu63Pro (p.L63P) ( ENST00000256474.3, ENST00000345392.3, ENST00000696143.2, ENST00000696153.1, ENST00000713811.1, ENST00000713812.1, ENST00000713815.1, ENST00000713982.1 )
VHL p.Leu63Pro (p.L63P) ( ENST00000256474.3, ENST00000345392.3, ENST00000696143.2, ENST00000696153.1, ENST00000713811.1, ENST00000713812.1, ENST00000713815.1, ENST00000713982.1 )
Associated Disease
pheochromocytoma
Source Database
ClinVar
Description
NM_000551.4(VHL):c.188T>C (p.Leu63Pro) AND Pheochromocytoma
ClinVar Allele ID
17266
ClinVar RefSeq Alternation Syntax
NM_198156.3:c.188T>C
ClinVar RefSeq Alternation Syntax
NM_001354723.2:c.188T>C
ClinVar RefSeq Alternation Syntax
NM_000551.4:c.188T>C
Clinical Significance Description
Pathogenic
Clinical Significance Last Update
1998-07-29
Clinical Significance Review Status
no assertion criteria provided
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000002315
ClinVar Disease
Pheochromocytoma
Observed Origin Sample
germline
Pubmed
9663592
Drugs