Annotation Detail
Information
- Associated Genes
- TUBB3
- Associated Variants
-
TUBB3 EXPRESSION
TUBB3 EXPRESSION - Associated Disease
- breast cancer
- Source Database
- CIViC Evidence
- Description
- High expression of betaIII-tubulin, as assessed in 85 breast cancers by IHC, was associated with better pathological response.
- Variant Origin
- N/A
- Variant Origin
- N/A
- Evidence URL
- https://civic.genome.wustl.edu/links/evidence_items/921
- Gene URL
- https://civic.genome.wustl.edu/links/genes/8262
- Variant URL
- https://civic.genome.wustl.edu/links/variants/389
- Rating
- 2
- Evidence Type
- Predictive
- Disease
- Breast Cancer
- Evidence Direction
- Supports
- Drug
- Taxane Compound
- Evidence Level
- B
- Clinical Significance
- Sensitivity/Response
- Pubmed
- 23218766
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Taxane Compound | Sensitivity | true |