Annotation Detail
Information
- Associated Genes
- PIK3CA
- Associated Variants
-
PIK3CA AMPLIFICATION
(
ENST00000263967.4 )
PIK3CA AMPLIFICATION ( ENST00000263967.4, ENST00000497599.5 ) - Associated Disease
- gastric adenocarcinoma
- Source Database
- CIViC Evidence
- Description
- In patients with gastric cancer, those with amplification of PIK3CA had shorter overall survival than those without amplification.
- Variant Origin
- somatic
- Variant Origin
- Somatic
- Evidence URL
- https://civic.genome.wustl.edu/links/evidence_items/504
- Gene URL
- https://civic.genome.wustl.edu/links/genes/37
- Variant URL
- https://civic.genome.wustl.edu/links/variants/212
- Rating
- 3
- Evidence Type
- Prognostic
- Disease
- Gastric Adenocarcinoma
- Evidence Direction
- Supports
- Evidence Level
- B
- Clinical Significance
- Poor Outcome
- Pubmed
- 22292935
Drugs