Annotation Detail
Information
- Associated Genes
- EGFR
- Associated Variants
-
EGFR AMPLIFICATION
(
ENST00000275493.7 )
EGFR AMPLIFICATION ( ENST00000275493.7 ) - Associated Disease
- Barrett's adenocarcinoma
- Source Database
- CIViC Evidence
- Description
- In patients with Barrett's adenocarcinoma, those with amplification of EGFR had shorter disease-specific survial.
- Variant Origin
- somatic
- Variant Origin
- Somatic
- Evidence URL
- https://civic.genome.wustl.edu/links/evidence_items/470
- Gene URL
- https://civic.genome.wustl.edu/links/genes/19
- Variant URL
- https://civic.genome.wustl.edu/links/variants/190
- Rating
- 3
- Evidence Type
- Prognostic
- Disease
- Barrett's Adenocarcinoma
- Evidence Direction
- Supports
- Evidence Level
- B
- Clinical Significance
- Poor Outcome
- Pubmed
- 20840671
Drugs