Annotation Detail
Information
- Associated Genes
- CEBPA
- Associated Variants
-
CEBPA MUTATION
CEBPA MUTATION - Associated Disease
- acute myeloid leukemia
- Source Database
- CIViC Evidence
- Description
- In a set of 315 pediatric patients with acute myeloid leukemia, 47 had mutations in CEBPA. Those with mutations had better overall survival than wild-type patients.
- Variant Origin
- somatic
- Variant Origin
- Somatic
- Evidence URL
- https://civic.genome.wustl.edu/links/evidence_items/468
- Gene URL
- https://civic.genome.wustl.edu/links/genes/15
- Variant URL
- https://civic.genome.wustl.edu/links/variants/29
- Rating
- 4
- Evidence Type
- Prognostic
- Disease
- Acute Myeloid Leukemia
- Evidence Direction
- Supports
- Evidence Level
- B
- Clinical Significance
- Better Outcome
- Pubmed
- 25014773
Drugs