Annotation Detail
Information
- Associated Genes
- IDH1
- Associated Variants
-
IDH1 R132
IDH1 R132 - Associated Disease
- myelodysplastic syndrome
- Source Database
- CIViC Evidence
- Description
- IDH1 R132 mutation in patients suffering from myelodysplastic syndromes is associated with worse overall survival.
- Variant Origin
- somatic
- Variant Origin
- Somatic
- Evidence URL
- https://civic.genome.wustl.edu/links/evidence_items/374
- Gene URL
- https://civic.genome.wustl.edu/links/genes/26
- Variant URL
- https://civic.genome.wustl.edu/links/variants/58
- Rating
- 4
- Evidence Type
- Prognostic
- Disease
- Myelodysplastic Syndrome
- Evidence Direction
- Supports
- Evidence Level
- B
- Clinical Significance
- Poor Outcome
- Pubmed
- 20494930
Drugs