Annotation Detail
Information
- Associated Genes
- IDH1
- Associated Variants
-
IDH1 R132
IDH1 R132 - Associated Disease
- malignant astrocytoma
- Source Database
- CIViC Evidence
- Description
- In patients with astrocytoma, the presence of IDH1 R132 mutation is prognostic for better survival compared to patients who harbor wild type mutation.
- Variant Origin
- somatic
- Variant Origin
- Somatic
- Evidence URL
- https://civic.genome.wustl.edu/links/evidence_items/348
- Gene URL
- https://civic.genome.wustl.edu/links/genes/26
- Variant URL
- https://civic.genome.wustl.edu/links/variants/58
- Rating
- 3
- Evidence Type
- Prognostic
- Disease
- Astrocytoma
- Evidence Direction
- Supports
- Evidence Level
- B
- Clinical Significance
- Better Outcome
- Pubmed
- 19933982
Drugs