Annotation Detail

Information
Associated Genes
GLA
Associated Variants
GLA MUTATION
GLA MUTATION
Associated Disease
Renal Insufficiency
Source Database
DisGeNET
Description
Fabry disease results from deficient α-galactosidase A activity and globotriaosylceramide accumulation causing renal insufficiency, strokes, hypertrophic cardiomyopathy and early demise.
Pubmed
25795794
Section of the abstract supporting the evidence
BACKGROUND
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs