Annotation Detail

Information
Associated Genes
PCSK9
Associated Variants
PCSK9 p.Gly670Glu (p.G670E) ( ENST00000673903.1, ENST00000710286.1, ENST00000713786.1, ENST00000302118.5 )
PCSK9 p.Gly670Glu (p.G670E) ( ENST00000302118.5, ENST00000673903.1, ENST00000710286.1, ENST00000713786.1 )
Associated Disease
Coronary Arteriosclerosis
Source Database
DisGeNET
Description
A common PCSK9 haplotype, encompassing the E670G coding single nucleotide polymorphism, is a novel genetic marker for plasma low-density lipoprotein cholesterol levels and severity of coronary atherosclerosis.
Pubmed
15893176
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00996740439685053
Year of publication
2005
Drugs