Annotation Detail

Information
Associated Genes
LRRK2
Associated Variants
LRRK2 p.Gly2385Arg (p.G2385R) ( ENST00000298910.12, ENST00000680790.1 )
LRRK2 p.Gly2385Arg (p.G2385R) ( ENST00000298910.12, ENST00000680790.1 )
Associated Disease
Parkinsonian Disorders
Source Database
DisGeNET
Description
The leucine-rich repeat kinase 2 (Lrrk2) G2385R substitution is associated with familial parkinsonism, late-, and early-onset Parkinson's disease in ethnic Chinese Taiwanese.
Pubmed
17222580
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.159157150231213
Year of publication
2007
Drugs