Annotation Detail

Information
Associated Genes
PCSK9
Associated Variants
PCSK9 p.Ser127Arg (p.S127R) ( ENST00000713786.1, ENST00000710286.1, ENST00000673903.1, ENST00000302118.5 )
PCSK9 p.Phe216Leu (p.F216L) ( ENST00000302118.5, ENST00000673903.1, ENST00000710286.1, ENST00000713786.1 )
PCSK9 p.Asp374Asn (p.D374N) ( ENST00000302118.5, ENST00000673903.1, ENST00000710286.1, ENST00000713786.1 )
PCSK9 p.Asp374Tyr (p.D374Y) ( ENST00000713786.1, ENST00000673903.1, ENST00000710286.1, ENST00000302118.5 )
PCSK9 p.Ser127Arg (p.S127R) ( ENST00000302118.5, ENST00000673903.1, ENST00000710286.1, ENST00000713786.1 )
PCSK9 p.Phe216Leu (p.F216L) ( ENST00000302118.5, ENST00000673903.1, ENST00000710286.1, ENST00000713786.1 )
PCSK9 p.Asp374Asn (p.D374N) ( ENST00000302118.5, ENST00000673903.1, ENST00000710286.1, ENST00000713786.1 )
PCSK9 p.Asp374Tyr (p.D374Y) ( ENST00000302118.5, ENST00000673903.1, ENST00000710286.1, ENST00000713786.1 )
Associated Disease
Hypercholesterolemia, autosomal dominant, 3
Source Database
DisGeNET
Description
NA
Original source reporting the Gene Disease association
CLINVAR
DisGENET score for the Gene Disease association
0.36
Year of publication
NA
Drugs